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Pesticide in Water Calculator Version 1.50 and 1.52 User Manual

The Pesticide in Water Calculator (PWC) is a water model used by OPP to estimate pesticide concentrations in water bodies that result from pesticide applications to land. Pesticide in Water Calculator...

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Guidance on Light-Dependent Peroxidizing Herbicides: Use of the Molar...

EPA has developed the following guidance for light-dependent peroxidizing herbicides (LDPHs) and other chemicals that may act via a light dependent peroxidizing (LDP) mode of action. The purpose of...

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PFAM 2.0 - Documentations

PFAM is an aquatic model used to estimate surface water exposure from the use of pesticides in flooded fields. In comparison to the Tier 1 rice model, PFAM allows for more advanced evaluation of...

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Food Contact Sanitizing Solutions Model (FCSSM)

The Food Contact Sanitizing Solutions Model (FCSSM) was developed to estimate indirect dietary exposure to components of sanitizing solutions used in commercial settings. Sanitizing solutions are...

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FCSSM User Guide and Supporting Documents

The Food Contact Sanitizing Solutions Model (FCSSM) was developed to estimate indirect dietary exposure to components of sanitizing solutions used in commercial settings.  FCSSM User Guide (PDF)(18 pp,...

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Developmental Neurotoxicity Study Guidance

EPA and Health Canada have developed new guidance for interpreting developmental neurotoxicity (DNT) data in support of a pesticide registration. The DNT study assesses behavioral and neurobiological...

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Exposure Surrogate Reference Table for Pesticide Risk Assessment - Previous...

The Exposure Surrogate Reference Table provides pesticide exposure information for risk assessment based on exposure scenarios, exposure routes and applicable personal protective equipment. The current...

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Supplemental Documents for November 19-22, 2019 SAP Meeting

EPA is presenting Approaches for Quantitative Use of Surface Water Monitoring Data in Pesticide Drinking Water Assessments to a FIFRA Scientific Advisory Panel on November 19 - 22, 2019. The primary...

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Summary of September 2019 Updates to Aquatic Life Benchmarks Table

EPA updated Aquatic Life Benchmarks table (view Aquatic Life Benchmarks and Ecological Risk Assessments for Registered Pesticides) as of September 30, 2019.  Updates to the aquatic life benchmarks...

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Documents on PCA/PCT and New Scenario Methods for Estimating Pesticide...

PCA/PCT and New Scenario Proposed Methodology and supporting documents.  EPA is accepting public comments on these new methods until February 29, 2020, via the following email address:...

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Rodenticide Study Protocols

EPA has provided the following 26 rodenticide study protocols to evaluate studies submitted by rodenticide manufacturers to support new rodenticide baits and tracking powders containing registered...

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Adopting 21st-Century Science Methodologies - Reduction Strategies

One of EPA’s goals is to reduce laboratory animal studies while maintaining the scientific rigor of pesticide assessments. EPA published its Guiding Principles for Data Requirements on May 31, 2013, to...

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Adopting 21st-Century Science Methodologies - Replacement Strategies

One of EPA’s goals is to replace complex laboratory animal studies with new approach methodologies (NAMs) while maintaining the scientific defensibility of pesticide assessments. NAMs include...

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Adopting 21st-Century Science Methodologies—Metrics

On Sept, 10, 2019, EPA Administrator Andrew Wheeler issued a directive to prioritize efforts to reduce animal testing, which included the goals of reducing mammal study requests and funding 30 percent...

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How EPA Receives Data for Pesticide Regulatory Decisions

Under the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA), applicants for pesticide registration (i.e., applicants) must demonstrate whether using the pesticide according to label...

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Framework for Conducting Pesticide Drinking Water Assessments for Surface Water

EPA developed this framework to document the long- standing practices that the Office of Pesticide Programs uses to conduct drinking water assessments for conventional pesticides in surface water....

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Guidance for Using Daily Average Aquatic Concentrations in Ecological...

This memorandum updates the approach EFED uses to calculate acute estimated environmental concentrations (EECs) for ecological assessments and acute estimated drinking water concentrations (EDWCs) for...

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Science Advisory Council for Exposure (ExpoSAC) Policy 3 Revised March 2021

This policy presents transfer coefficients (TC) for agricultural or commercial activities for use in post-application exposure assessments. ExpoSAC Policies 10 (Personal Protective Equipment Use by...

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